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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T70695 | CP 100356 | ||
CP 100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. The compound has low uM to nM potency for inhibiting several MDR-1 substrates (calcein-AM, digoxin) in transfected MDCKII cells. | |||
T22680 | CP-100356 hydrochloride | CP-100356 HCl,CP 100356 hydrochloride | BCRP |
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory effects on MDR1-mediated Calcein-AM transporter and BCRP-medi... | |||
T70693 | MRT-92 HCl salt | ||
MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell prolifera... |